
- Episode 1 Bob Woodward, Luke Combs Stephen welcomes journalist Bob Woodward and a musical performance by Luke Combs.
- Episode 2 Janelle Monae, Jacob Soboroff Stephen welcomes signer Janelle Monae and journalist Jacob Soboroff.
- Episode 3 Drew Barrymore, Lang Lang Stephen welcomes actress Drew Barrymore and a musical performance by Lang Lang.
- Episode 4 Sarah Paulson, PJ Morton Stephen welcomes actress Sarah Paulson and a musical performance by PJ Morton.
- Episode 5 Moment of Ruth Stephen welcomes Lt. Gen. H.R. McMaster and actor Laurence Fishburne.
- Episode 6 Desus Nice, The Kid Mero, Jake Isaac Stephen welcomes TV hosts Desus Nice and The Kid Mero, and a musical performance by Jake Isaac.
- Episode 7 Jeff Daniels, Yusuf / Cat Stevens Stephen welcomes actor Jeff Daniels and a performance by Yusuf / Cat Stevens.
- Episode 8 Rep. Katie Porter, Tony Romo Stephen welcomes Rep. Katie Porter and sports analyst Tony Romo.
- Episode 9 Mariah Carey, Rex Orange County Stephen welcomes singer Mariah Carey and a musical performance by Rex Orange County.
- Episode 10 Cory Booker, Public Enemy Stephen welcomes Senator Cory Booker and a musical performance by Public Enemy.
- Episode 11 John Lithgow, Jonathan Alter Stephen welcomes actor John Lithgow and journalist Jonathan Alter.
- Episode 12 Fears of a Clown Stephen welcomes actor Ethan Hawke and Prosecutor Andrew Weissmann.
- Episode 13 Dr. Jon LaPook, John Dickerson Stephen welcomes CBS News Chief Medical Correspondent Dr. LaPook and CBS News political analyst John Dickerson.
- Episode 14 Jon Bon Jovi Stephen welcomes singer Jon Bon Jovi for an interview and a musical performance.
- Episode 15 Jerry Seinfeld, Ella Mai Stephen welcomes actor Jerry Seinfeld and a musical performance by Ella Mai.
- Episode 16 Pete Buttigieg, Future Islands Stephen welcomes Mayor Pete Buttigieg and a musical performance by Future Islands.
- Episode 17 Kamala Drops the Mike! Stephen welcomes actress Mindy Kaling and Former CIA Director John Brennan.
- Episode 18 West Winging It! Stephen welcomes the stars and creator of “The West Wing”: Allison Janney, Richard Schiff, Martin Sheen, Bradley Whitford, and Aaron Sorkin.
- Episode 19 Joy Reid, Yahya Abdul-Mateen II Stephen welcomes television host Joy Reid and actor Yahya Abdul-Mateen II.
- Episode 20 Dolly Parton, Ty Dolla $ign Stephen welcomes singer Dolly Parton and a musical performance by Ty Dolla $ign.
- Episode 21 Bruce Springsteen, Eva Longoria Stephen welcomes singer-songwriter Bruce Springsteen and actress Eva Longoria.
- Episode 22 Andrew Cuomo, Matt Berninger Stephen welcomes Governor Andrew Cuomo and a musical performance by Matt Berninger.
- Episode 23 Campaign Trail Mix The Late Show with Stephen Colbert: 2020 Campaign Coverage Special hosted by Sam Waterston.
- Episode 24 Sacha Baron Cohen, Jeff Tweedy Stephen welcomes actor Sacha Baron Cohen and musician Jeff Tweedy.
- Episode 25 Dr. Sanjay Gupta, Sarah Cooper Stephen welcomes medial reporter Dr. Sanjay Gupta and author Sarah Cooper.
- Episode 26 Jaime Harrison, Elvis Costello Stephen welcomes politician Jaime Harrison, plus an interview with and a musical performance by Elvis Costello.
- Episode 27 Julie Andrews, Amy Walter, Sam Smith Stephen welcomes actress Julia Andrews, political analyst Amy Walter with a musical performance by Sam Smith.
- Episode 28 Jon Stewart, Neil deGrasse Tyson Stephen welcomes actor Jon Stewart and astrophysicist Neil deGrasse Tyson.
- Episode 29 John Oliver, Cher, Jojo Stephen welcomes TV Host John Oliver, singer Cher, plus a musical performance by Jojo.
- Episode 30 Shepard Smith, Leon Bridges, Lucky Daye Stephen welcomes CNBC's Chief general anchor Shepard Smith, and a musical performance by Leon Bridges and Lucky Daye.
- Episode 31 Larry Wilmore, Laura Benanti Stephen welcomes comedian Larry Wilmore and a musical performance by Laura Benanti.
- Episode 32 Alex Wagner, John Heilemann, Mark McKinnon, Charlamagne Tha God, Jena Friedman, Maz Jobrani, Arcade Fire Network presentation of The Late Show's Showtime Election Night Special, The hosts of "The Circus": Alex Wagner, John Heilemann and Mark McKinnon, Charlamagne Tha God, Jena Friedman, Maz Jobrani, and…
- Episode 33 Stacey Abrams, Thomas Middleditch Stephen welcomes politician Stacey Abrams and actor Thomas Middleditch.
- Episode 34 Hugh Grant, Sturgill Simpson Stephen welcomes actor Hugh Grant and singer Sturgill Simpson.
- Episode 35 Olivia Colman, Gillian Anderson, Kylie Minogue Stephen welcomes actress Olivia Colman, actress Gillian Anderson, singer Kylie Minogue.
- Episode 36 Michael Moore, Sara Bareilles, Steve Carell Stephen welcomes filmmaker Michael Moore, singer Sara Bareilles and a special appearance by actor Steve Carell.
- Episode 37 Jake Tapper, BENEE Stephen welcomes American Journalist Jake Tapper, and a musical performance by BENEE.
- Episode 38 Lewis Hamilton, Andrea Bocelli Stephen welcomes Formula 1 racing driver Lewis Hamilton, and a musical performance by Andrea Bocelli.
- Episode 39 11/18/20 (Matthew McConaughey, Cedric the Entertainer) Stephen welcomes actor Matthew McConaughey and actor Cedric the Entertainer.
- Episode 40 11/19/20 (LL Cool J, Dave Grohl, Foo Fighters) Stephen welcomes actor LL Cool J, from the CBS drama NCIS: Los Angeles, musician Dave Grohl and a musical performance by Foo Fighters.
- Episode 41 Glenn Close, Kane Brown, Swae Lee, Khalid Glenn Close, Kane Brown, Swae Lee, Khalid
- Episode 42 President Barack Obama, Brittany Howard
- Episode 43 Rob Corddry, John Lithgow, Chef José Andrés Rob Corddry, John Lithgow, Chef José Andrés
- Episode 44 President Barack Obama, Vol. 2 President Barack Obama, Vol. 2
- Episode 45 Bryan Cranston, Cori Bush Bryan Cranston, Cori Bush
- Episode 46 Kate Winslet, Michael Eric Dyson Kate Winslet, Michael Eric Dyson
- Episode 47 Christopher Krebs, Aubrey Plaza Christopher Krebs, Aubrey Plaza
- Episode 48 Common, Andrea Bocelli Common, Andrea Bocelli
- Episode 49 Meryl Streep, Chris Stapleton Meryl Streep, Chris Stapleton
- Episode 50 John Dickerson, Emily Bazelon, David Plotz, Greta Van Fleet John Dickerson, Emily Bazelon, David Plotz, Greta Van Fleet
- Episode 51 Rachel Maddow, Megan Thee Stallion Rachel Maddow, Megan Thee Stallion
- Episode 52 James Corden, Fleet Foxes James Corden, Fleet Foxes
- Episode 53 New Zealand Special New Zealand Special
- Episode 54 Chance The Rapper, Christopher Walken, Laura Benanti Chance The Rapper, Christopher Walken, Laura Benanti
- Episode 55 Whoopi Goldberg, Anderson Cooper, Andy Cohen Whoopi Goldberg, Anderson Cooper, Andy Cohen
- Episode 56 Tom Hanks, Leslie Odom Jr. Tom Hanks, Leslie Odom Jr.
- Episode 57 Joseph R. Biden, Dr. Jill Biden, Jon Batiste Joseph R. Biden, Dr. Jill Biden, Jon Batiste
- Episode 58 George Clooney George Clooney
- Episode 59 Stacey Abrams, RuPaul Charles, Maren Morris Stacey Abrams, RuPaul Charles, Maren Morris
- Episode 60 Dr. Sanjay Gupta, Anya Taylor-Joy Dr. Sanjay Gupta, Anya Taylor-Joy
- Episode 61 Amy Klobuchar, Adam Kinzinger, Jamila Woods Amy Klobuchar, Adam Kinzinger, Jamila Woods
- Episode 62 Rachel Brosnahan, Julien Baker Rachel Brosnahan, Julien Baker
- Episode 63 George Clooney, Tom Hanks, Meryl Streep, The Mountain Goats George Clooney, Tom Hanks, Meryl Streep, The Mountain Goats
- Episode 64 Chris Rock, Aubrey Plaza, Joss Stone Chris Rock, Aubrey Plaza, Joss Stone
- Episode 65 James Comey, Lili Reinhart James Comey, Lili Reinhart
- Episode 66 Samantha Bee, Paul Mescal Samantha Bee, Paul Mescal
- Episode 67 Bernie Sanders, FINNEAS Bernie Sanders, FINNEAS
- Episode 68 John Heilemann, Mark McKinnon & Alex Wagner, The War On Drugs John Heilemann, Mark McKinnon & Alex Wagner, The War On Drugs
- Episode 69 Cory Booker, Laura Benanti, Infinity Song Cory Booker, Laura Benanti, Infinity Song
- Episode 70 Jason Segel, Black Pumas Jason Segel, Black Pumas
- Episode 71 It’s Joe Time! Jon Lovett, Jon Favreau, Tommy Vietor, Peter CottonTale, Chance the Rapper, Cynthia Erivo, Chicago Children's Choir, Kofi Lost
- Episode 72 Priyanka Chopra Jonas, Derek DelGaudio, Frank Oz Priyanka Chopra Jonas, Derek DelGaudio, Frank Oz
- Episode 73 Serena Williams, Dayglow Stephen welcomes professional tennis player Serena Williams and a musical performance by Dayglow.
- Episode 74 Colin Firth, Stanley Tucci, Adrianne Lenker Stephen welcomes actor Colin Firth, actor Stanley Tucci, and a musical performance by Adrianne Lenker.
- Episode 75 Billy Crystal, Jackie Speier Stephen welcomes actor Billy Crystal and Rep. Jackie Speier (D-Calif.).
- Episode 76 Viggo Mortensen, Charles Blow Stephen welcomes actor Viggo Mortensen and journalist Charles Blow.
- Episode 77 Joe Biden, Jill Biden, Kamala Harris Stephen welcomes President Joe Biden, First Lady Jill Biden, and Vice President Kamala Harris.
- Episode 78 Ethan Hawke, Mickey Guyton Stephen welcomes actor Ethan Hawke and a musical performance by Mickey Guyton.
- Episode 79 Zendaya, James Martin Stephen welcomes actress Zendaya and Father James Martin.
- Episode 80 Salma Hayek, Mark Harris Stephen welcomes actress Salma Hayek and journalist Mark Harris.
- Episode 81 Tiffany Haddish, H.E.R. Stephen welcomes actress Tiffany Haddish and a musical performance by H.E.R.
- Episode 82 Robert Downey Jr., Tiffany Haddish, Metallica Stephen welcomes actor Robert Downey Jr., actress Tiffany Haddish, and a musical performance by Metallica.
- Episode 83 Queen Latifah, Steven Yeun Stephen welcomes actress Queen Latifah and actor Steven Yeun.
- Episode 84 John Oliver, Ingrid Andress Stephen welcomes TV host John Oliver and a musical performance by Ingrid Andress.
- Episode 85 Kristen Wiig, Rebecca Breeds Stephen welcomes actress Kristen Wiig and actress Rebecca Breeds.
- Episode 86 Blake Shelton Stephen welcomes a talk and musical performance by Blake Shelton.
- Episode 87 Bill Gates, Tune-Yards Stephen welcomes co-founder of Microsoft Bill Gates and a musical performance by Tune-Yards.
- Episode 88 Billie Eilish, Anna Palmer, Jake Sherman Stephen welcomes singer Billie Eilish, Punchbowl News Co-Founders Anna Palmer & Jake Sherman.
- Episode 89 Arsenio Hall, Tim Meadows, Celeste Stephen welcomes actor Arsenio Hall, actor Tim Meadows and a musical performance by Celeste.
- Episode 90 Regina King, Jamaal Bowman, Vic Mensa, Wyclef Jean, Peter Cottontale Stephen welcomes actress Regina King, a special appearance by Rep. Jamaal Bowman, and a musical performance by Vic Mensa featuring Wyclef Jean and Peter Cottontale.
- Episode 91 Andy Samberg, Clarissa Ward Stephen welcomes actor Andy Samberg and journalist Clarissa Ward.
- Episode 92 Neil deGrasse Tyson, Jon Batiste Stephen welcomes astrophysicist Neil deGrasse Tyson and a musical performance by Jon Batiste.
- Episode 93 Paul Bettany, Metallica Stephen welcomes actor Paul Bettany and a musical performance by Metallica.
- Episode 94 Jane Fonda, The Hosts of “Virtue Signal”, Kings of Leon Stephen welcomes actress Jane Fonda, the Hosts of “Virtue Signal”, and a musical performance by Kings of Leon.
- Episode 95 Nicolle Wallace, Michaela Coel, Kings of Leon Stephen welcomes TV host Nicolle Wallace, actress Michaela Coel, and a musical performance by Kings of Leon.
- Episode 96 Riz Ahmed, Janelle Monáe Stephen welcomes actor Riz Ahmed and a musical performance by Janelle Monáe.
- Episode 97 Emmanuel Acho, Gina Yashere Stephen welcomes sports analyst Emmanuel Acho and comedian Gina Yashere.
- Episode 98 Aaron Paul, Billy Crystal, Lake Street Dive Stephen welcomes actor Aaron Paul, actor Billy Crystal, and a musical performance by Lake Street Dive.
- Episode 99 Dr. Anthony Fauci Stephen welcomes Dr. Anthony Fauci.
- Episode 100 Ringo Starr, Laura Benanti Stephen welcomes musician Ringo Starr and a special appearance by actress Laura Benanti.
- Episode 101 Lupita Nyong’o, Martin Freeman Stephen welcomes actress Lupita Nyong’o and actor Martin Freeman.
- Episode 102 Earvin “Magic” Johnson, Eric Andre Stephen welcomes businessman Earvin “Magic” Johnson and comedian Eric Andre.
- Episode 103 Chuck Schumer, Jared Leto, LANCO Stephen welcomes Senator Chuck Schumer, actor Jared Leto and a musical performance by LANCO.
- Episode 104 Robert Downey Jr., Walter Isaacson, Sebastian Yatra, Guaynaa Stephen welcomes actor Robert Downey Jr., author Walter Isaacson, and a musical performance by Sebastian Yatra and Guaynaa.
- Episode 105 Dana Carvey, Imagine Dragons Stephen welcomes actor Dana Carvey and a musical performance by Imagine Dragons.
- Episode 106 Sharon Stone, Ken Burns Stephen welcomes actress Sharon Stone and filmmaker Ken Burns.
- Episode 107 John Cena, Tammy Duckworth Stephen welcomes TV host John Cena and Senator Tammy Duckworth.
- Episode 108 Ronan Farrow, Brandi Carlile Stephen welcomes journalist Ronan Farrow and singer Brandi Carlile.
- Episode 109 Leslie Odom Jr., Michio Kaku Stephen welcomes actor Leslie Odom Jr. and physicist Michio Kaku.
- Episode 110 Hank Azaria, Cheap Trick Stephen welcomes actor Hank Azaria and a musical performance by Cheap Trick.
- Episode 111 John Boehner, Shelley
- Episode 112 Daniel Kaluuya, Lucy Dacus, Taylor Swift
- Episode 113 Willie Geist, Maria Bakalova
- Episode 114 Amanda Seyfried, Ashley McBryde
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Episode 115
Anthony Hopkins, Florian Zeller, Mazie Hirono
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Episode 116
Cher, Bradley Whitford
Stephen welcomes singer Cher, and a musical performance by Sam Williams.
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Episode 117
Ed Helms, Susan Page
Stephen welcomes actor Ed Helms and journalist Susan Page.
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Episode 118
Joe Scarborough, Mika Brzezinski, Bebe Rexha
Stephen welcomes TV host Joe Scarborough, journalist Mika Brzezinski, and a musical performance by Bebe Rexha.
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Episode 119
Anthony Mackie, Terry Gross
Stephen welcomes actor Anthony Mackie and radio show host Terry Gross.
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Episode 120
Sen. Amy Klobuchar, Kyle MacLachlan
Stephen welcomes Senator Amy Klobuchar and actor Kyle MacLachlan.
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Episode 121
Sen. Bernie Sanders, Julia Michaels
Stephen welcomes Senator Bernie Sanders and a musical performance by Julia Michaels.
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Episode 122
Mila Kunis, Sara Kays
Stephen welcomes actress Mila Kunis and a musical performance by Sara Kays.
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Episode 123
Jane Fonda, John Oliver, Ringo Starr, Teddy Swims
Stephen welcomes actress Jane Fonda, TV personality John Oliver, musician Ringo Starr, and a musical performance by Teddy Swims.
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Episode 124
Jake Tapper, Billie Eilish
Stephen welcomes journalist Jake Tapper and musician Billie Eilish.
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Episode 125
Michelle Obama
Stephen welcomes former first lady Michelle Obama.
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Episode 126
Elizabeth Warren, David Boreanaz
Stephen welcomes Senator Elizabeth Warren and actor David Boreanaz.
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Episode 127
Seth Rogen, Jack Ingram, Miranda Lambert, Jon Randall
Stephen welcomes actor Seth Rogen and a musical performance by Jack Ingram, Miranda Lambert & Jon Randall.
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Episode 128
Billy Crystal, Tiffany Haddish, The Black Keys
Stephen welcomes actors Billy Crystal & Tiffany Haddish and a musical performance by The Black Keys.
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Episode 129
Cindy McCain, MJ Rodriguez
Stephen welcomes businesswoman Cindy McCain and actress MJ Rodriguez.
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Episode 130
Morgan Freeman, Tig Notaro
Stephen welcomes actor Morgan Freeman and comic Tig Notaro.
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Episode 131
Lisa Kudrow, Tamika Mallory
Stephen welcomes actress Lisa Kudrow and activist Tamika Mallory.
- Episode 132 John Krasinski, Yo-Yo Ma Stephen welcomes actor John Krasinski and a musical performance by Yo-Yo Ma.
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Episode 133
Anthony Anderson, Dr. Francis Collins
Stephen welcomes actor Anthony Anderson and Dr. Francis Collins.
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Episode 134
Gayle King, BTS
Stephen welcomes journalist Gayle King and a musical performance by BTS.
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Episode 135
Will Arnett, Brockhampton
Stephen welcomes actor Will Arnett and a musical performance by Brockhampton.
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Episode 136
Bradley Whitford, Carlos Watson
Stephen welcomes actor Bradley Whitford and journalist Carlos Watson.
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Episode 137
Chris Matthews, Cynthia Erivo
Stephen welcomes journalist Chris Matthews and a musical performance by Cynthia Erivo.
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Episode 138
Clive Owen, Ziwe
Stephen welcomes actor Clive Owen and comic Ziwe.
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Episode 139
Samuel L. Jackson, Padma Lakshmi
Stephen welcomes actor Samuel L. Jackson and TV personality Padma Lakshmi.
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Episode 140
Samantha Power, Maroon 5, Seth Rogen
Stephen welcomes USAID Administrator Samantha Power, a musical performance by Maroon 5, and special appearance by Seth Rogen.
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Episode 141
Jon Stewart, Jon Batiste, Dana Carvey
Stephen welcomes comic Jon Stewart, a musical performance by Jon Batiste, and a special appearance by Dana Carvey.
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Episode 142
Dr. Sanjay Gupta, Rita Moreno
Stephen welcomes Dr. Sanjay Gupta and actress Rita Moreno.
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Episode 143
Anderson Cooper, Sleater-Kinney
Stephen welcomes journalist Anderson Cooper and a musical performance by Sleater-Kinney.
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Episode 144
Nathan Lane, Griff
Stephen welcomes actor Nathan Lane and a musical performance by Griff.
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Episode 145
Andrew Garfield, Lorde
Stephen welcomes actor Andrew Garfield and singer Lorde.
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Episode 146
Wanda Sykes, Craig Melvin
Stephen welcomes actress Wanda Sykes and journalist Craig Melvin.
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Episode 147
Christine Baranski, Joy Oladokun
Stephen welcomes actress Christine Baranski and a musical performance by Joy Oladokun.
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Episode 148
Robert Duvall
Stephen welcomes actor Robert Duvall.
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Episode 149
Pete Buttigieg, Katja Herbers
Stephen welcomes secretary Pete Buttigieg and actress Katja Herbers.
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Episode 150
Vin Diesel, Helen Mirren, Ludacris, John Cena, Tyrese Gibson, Justin Lin, Jordana Brewster, Dominic Monaghan, Billy Boyd
Stephen welcomes the cast of F9: Vin Diesel, Helen Mirren, Ludacris, John Cena, Tyrese Gibson, Justin Lin, Jordana Brewster; actors Dominic Monaghan and Billy Boyd and a comedic performance by…
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Episode 151
Harvey Keitel, Randall Otis
Stephen welcomes actor Harvey Keitel and comic Randall Otis.
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Episode 152
Jim Gaffigan, JP Saxe with John Mayer
Stephen welcomes comic Jim Gaffigan and a musical performance by JP Saxe & John Mayer.
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Episode 153
Keegan-Michael Key, Tones and I
Stephen welcomes actor Keegan-Michael Key and a musical performance by Tones And I.
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Episode 154
Richard Branson, Rep. Eleanor Holmes Norton
Stephen welcomes sir Richard Branson and Rep. Eleanor Holmes Norton.
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Episode 155
Mindy Kaling, Wally Baram
Stephen welcomes actress Mindy Kaling and writer Wally Baram.
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Episode 156
Coup Close For Comfort!
Stephen welcomes actor Hugh Jackman and a musical performance by Lorde.
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Episode 157
Joy Reid, Alessia Cara
Stephen welcomes TV host Joy Reid and a musical performance by Alessia Cara.
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Episode 158
Jason Sudeikis, Yola
Stephen welcomes actor Jason Sudeikis and a musical performance by Yola.
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Episode 159
Emily Blunt, Bob Costas
Stephen welcomes actress Emily Blunt and sportscaster Bob Costas.
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Episode 160
Hannah Einbinder, Alex Falcone
Stephen welcomes actress Hannah Einbinder and comic Alex Falcone.
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Episode 161
Stephen King, Winston Duke
Stephen welcomes author Stephen King and actor Winston Duke.
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Episode 162
Brian Stelter, Big Red Machine
Stephen welcomes news correspondent Brian Stelter and a musical performance by Big Red Machine.
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Episode 163
Planes, Trains & Bipartisan Deals!
Stephen welcomes actor Alan Alda and comic Gabriel Iglesias.
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Episode 164
Jennifer Hudson
Stephen welcomes an interview with and musical performance by Jennifer Hudson.
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Episode 165
Dr. Jonathan Lapook, Fumi Abe
Stephen welcomes Dr. Jonathan Lapook and comic Fumi Abe.
- Episode 166 Amanda Peet, Roger Bennett Stephen welcomes actress Amanda Peet and journalist Roger Bennett.
- Episode 167 Three-For-All! Stephen welcomes actor Daniel Radcliffe and a musical performance by Dan + Shay.
- Episode 168 Sean & Dylan Penn, Crowded House Stephen welcomes actors Sean & Dylan Penn and a musical performance by Crowded House.